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A new weight-loss drug that contains anti-addiction drug naltrexone continues to be approved by the U.S. Food and Drug Administration today, the business said in the statement.

Using two separate drugs to shed pounds can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with fat loss and the people who go through it you need to err assisting caution and allow FDA do its job and demand some study be done so that the public recognizes the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies come in business to generate income and that they would say everything to keep people on their own medications.

Researchers discovered that participants investing in this drug for a year, dropped excess weight within four weeks and have kept the load off throughout the 56 weeks of the study. Contrave is a combination in the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs that are made up of more than one active ingredient, which can make them more effective and safer.

Combo-pilling will be the newest fad or in addition to this the newest ahead under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular will be the fact that by right now there are not any long term prescription weightloss pills that have been approved by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures really are a side effect with Contrave and must not be taken in those with seizure disorders. The drug could also raise blood pressure levels and heart rate, and really should not be used in people who have a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must 't be used in patients with uncontrolled high blood pressure level, and also by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients having a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients on the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.


"There were no signs and symptoms of depression or suicidal thoughts in trial participants," said Fujioka.